This study investigates the preparation of mPEG-PLA diblock copolymers through a controlled chemical process. Various reaction conditions, including temperature, were optimized to achieve desired molecular weights and polydispersity indices. The resulting copolymers were examined using techniques such as size exclusion chromatography (SEC), nuclear

Poly(lactic acid) PLA (PLA) is a versatile biocompatible polymer widely used in drug delivery systems. However, its rapid degradation and poor water solubility limit its efficacy. To overcome these challenges, PEGylation, the process of attaching polyethylene glycol Polyethylene Glycol, has emerged as a promising strategy. Biocompatible PEGylation